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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR2
All Species:
14.55
Human Site:
S452
Identified Species:
32
UniProt:
P21802
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21802
NP_000132.3
821
92025
S452
V
R
I
T
T
R
L
S
S
T
A
D
T
P
M
Chimpanzee
Pan troglodytes
XP_521622
819
91776
T452
I
T
T
R
L
S
S
T
A
D
T
P
M
L
A
Rhesus Macaque
Macaca mulatta
XP_001106418
825
91775
P463
L
S
S
T
A
D
T
P
M
L
A
G
V
S
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P21803
821
91965
S452
V
R
I
T
T
R
L
S
S
T
A
D
T
P
M
Rat
Rattus norvegicus
Q04589
822
91806
S451
V
R
P
S
R
L
S
S
S
G
T
P
M
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18461
823
92281
S454
V
R
I
T
T
R
L
S
S
T
A
D
A
P
M
Frog
Xenopus laevis
Q03364
813
91322
E457
L
A
N
V
S
E
Y
E
L
P
H
D
P
M
W
Zebra Danio
Brachydanio rerio
Q8JG38
817
91370
S452
V
R
I
T
T
R
R
S
S
A
H
D
D
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09147
1052
117795
Q676
P
V
I
R
I
E
K
Q
R
T
T
V
S
T
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
I595
D
E
P
S
P
Y
Q
I
Q
I
I
E
T
P
I
Sea Urchin
Strong. purpuratus
Q26614
972
110463
R611
I
A
P
L
F
G
G
R
N
R
L
T
S
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
88.3
N.A.
N.A.
96.9
71.7
N.A.
N.A.
92.8
77.5
77.4
N.A.
29
N.A.
31.6
34.4
Protein Similarity:
100
99.6
90.9
N.A.
N.A.
98.1
83.8
N.A.
N.A.
96.3
87.2
86.5
N.A.
45.1
N.A.
46.5
51.7
P-Site Identity:
100
0
13.3
N.A.
N.A.
100
26.6
N.A.
N.A.
93.3
6.6
66.6
N.A.
13.3
N.A.
13.3
0
P-Site Similarity:
100
20
20
N.A.
N.A.
100
33.3
N.A.
N.A.
93.3
20
73.3
N.A.
20
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
10
0
0
0
10
10
37
0
10
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
10
0
0
0
10
0
46
10
0
0
% D
% Glu:
0
10
0
0
0
19
0
10
0
0
0
10
0
0
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
10
0
0
10
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% H
% Ile:
19
0
46
0
10
0
0
10
0
10
10
0
0
0
19
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
19
0
0
10
10
10
28
0
10
10
10
0
0
19
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
19
10
28
% M
% Asn:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
10
0
28
0
10
0
0
10
0
10
0
19
10
46
0
% P
% Gln:
0
0
0
0
0
0
10
10
10
0
0
0
0
0
0
% Q
% Arg:
0
46
0
19
10
37
10
10
10
10
0
0
0
0
0
% R
% Ser:
0
10
10
19
10
10
19
46
46
0
0
0
19
19
0
% S
% Thr:
0
10
10
46
37
0
10
10
0
37
28
10
28
10
10
% T
% Val:
46
10
0
10
0
0
0
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _